Working on the FightAIDS@Home project involves downloading and installing a free software package, provided by the Olson Laboratory. The software uses spare capacity on the computer to identify potential drugs that have the right shape and chemical properties to block HIV protease. This is an enzyme that plays a key role in the infection of cells by HIV, so inhibiting its action disrupts the ability of the virus to spread throughout the infected person.

Scale of the AIDS Problem Worldwide

Since the AIDS epidemic began twenty years or so ago, more than 60 million people have been infected with the human immunodeficiency virus (HIV). According to UNAIDS, between 2000 and 2020 about 68 million people will die prematurely as a result of AIDS. Most of this death toll will be in sub-Saharan Africa. Currently the life expectancy there is about 47 years. Without the effect of AIDS it would be 62 years.

Children and young people are the hardest-hit by the epidemic, with more than 14 million children being orphaned so far. It is estimated that the world community will need to spend $25 billion on AIDS services in 2010.

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